Blood Loss

Blood Loss is a negative buff that is applied when using a Blood Draw Kit multiple times in quick succession. While at first it only drains Stamina, applying the Blood Draw Kit again will cause the debuff duration to lengthen and draw on Wellness.

Generally, it can be avoided by simply not using Blood Draw Kits in quick succession (less than 2.5 minutes interval).

Mechanics
User Killermoench explains mechanic (alpha 15.1) on Steam Forum as follows (edited by Zacha for better english and structure)(edited again by Commander Shades for grammar and structure):
 * Blood Draw Kit raises the bloodloss value by 150. Bloodloss value decreases by 10 every 10 seconds. If bloodloss value is greater than 150 you lose 0.5 stamina per second until bloodloss value is equal to or less than 150. If it is greater than 300 you lose 2 stamina per second and 0.6 wellness per minute until bloodloss is equal to or less than 300.


 * So this means that if you use Blood Draw Kit every 150 seconds, you only have HP reduction. When you use the Blood Draw Kit a second time before 150 seconds have passed, then comes the first drawback with stamina loss (Blood Loss). With a third use before the first 150 seconds run out, the second drawback comes with an additional wellness loss (Blood Loss Advanced).